Article
Phenotypic diversity in delayed drug hypersensitivity: an immunologic explanation.
The Mount Sinai journal of medicine, New York - 1 Sept 2006
Meth Marc J, Sperber Kirk E
Abstract excerpt
Drug hypersensitivity reactions are a significant cause of iatrogenic-induced illness. (They were originally classified as type IV hypersensitivity, to describe the tuberculin skin reaction.) It now appears that the T-cell directs the entire inflammatory cascade induced by delayed drug allergy. Delayed drug hypersensitivity, usually manifested in the skin, is triggered when drug-specific CD4+ and CD8+ T cells...
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