Article

Elucidating CD4+ and CD8+ T-cell involvement in patients with vancomycin-induced DRESS.

2024-12-17

Abstract excerpt

<h4>Background: </h4> Vancomycin, a glycopeptide antibiotic routinely used to treat severe Gram-positive bacterial infections, is associated with the development of drug reaction with eosinophilia and systemic symptoms (DRESS) in individuals expressing HLA-A*32:01. Previous studies have identified the potential role of T-cells using HLA-A*32:01 positive healthy donor models. However, DRESS pathogenesis remains poo...

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Literature Corpus work: ced01605-7b33-575a-aad0-76b23e246ec5
DOI: 10.22541/au.173444611.15412515/v1

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