Article

C5aR1 inhibition alleviates cranial radiation-induced cognitive decline

2024-07-04

Abstract excerpt

<h4>ABSTRACT</h4> Cranial radiation therapy (RT) for brain cancers leads to an irreversible decline in cognitive function without an available remedy. Radiation-induced cognitive deficits (RICD) are a particularly pressing problem for the survivors of pediatric and low grade glioma (LGG) cancers who often live long post-RT lives. Radiation-induced elevated neuroinflammation and gliosis, triggered by the detriment...

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Literature Corpus work: 6d68a3e2-65e8-5e97-b453-50a01e647015
DOI: 10.1101/2024.07.02.601806

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