Article

Lowering glucose enhances BACE1 activity and Aβ generation in mouse brain slice cultures

2024-03-14

Abstract excerpt

Numerous environmental risk factors are now recognised as contributors to the onset and progression of Alzheimer’s disease (AD). It is probable that, in most instances, AD arises from a combination of genetic predisposition and environmental influences. In particular, there is a strong correlation between vascular impairment and dementia, yet the specific mechanisms by which vascular impairment and AD are linked,...

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Literature Corpus work: 6d4f358f-10a5-5a09-aa19-f906fe1e9bb3
DOI: 10.1101/2024.03.12.584616

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