Article
Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin.
The Journal of cell biology - 6 Oct 2008
Kunwar Prabhat S, Sano Hiroko, Renault Andrew D, Barbosa Vitor, Fuse Naoyuki, Lehmann Ruth
Abstract excerpt
Despite significant progress in identifying the guidance pathways that control cell migration, how a cell starts to move within an intact organism, acquires motility, and loses contact with its neighbors is poorly understood. We show that activation of the G protein-coupled receptor (GPCR) trapped in endoderm 1 (Tre1) directs the redistribution of the G protein Gbeta as well as adherens junction proteins and Rho...
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