BiGen: Integrative Clinical and Brain-Imaging Genetics Analysis Using Structural Equation Model

Abstract excerpt

The identification of genetic variants associated with complex brain diseases has evolved in the past decades. Studies in the field have taken different approaches and study designs including genome-wide association studies. Neuroimaging and connectomics have also improved our understanding of the structural connectivity of the human brain and produced reliable measurements. Combining both neuroimaging and genetic...

Topics

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• Advanced Neuroimaging Techniques and Applications
• Alzheimer Disease
• Connectome
• Gene Ontology
• Gene Regulatory Networks
• Insulin-Like Growth Factor I
• Receptors, G-Protein-Coupled
• Receptors, Peptide

Identifiers and source

Literature Corpus work

6d2174a8-11a2-5b7b-86c6-a381b4d66ae5

DOI

10.1101/2020.02.04.934596