Article

MSI2 regulates NLK-mediated EMT and PI3K/AKT/mTOR pathway to promote pancreatic cancer progression

2024-02-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>The incidence of pancreatic cancer is increasing by years, and the 5-year survival rate is very low. Our team have revealed that Musashi2 (MSI2) could promote aggressive behaviors in pancreatic cancer by downregulating Numb and p53. MSI2 also facilitates EMT in pancreatic cancer induced by EGF through the ZEB1-ERK/MAPK signaling pathway. This study aims to furth...

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Literature Corpus work: 6d0e6a1b-4b5c-5a49-a79b-dfdc6b2e53cb
DOI: 10.21203/rs.3.rs-3963270/v1

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