Article

The landscape of tertiary lymphoid structures in endometrial cancer revealed through harmonized multi-level transcriptomics

2025-08-23

Abstract excerpt

<h4>Summary</h4> Tertiary lymphoid structures (TLSs) are ectopic lymphoid tissues that form within tumors. TLSs are associated with improved prognosis and better responses to immune checkpoint inhibitors (ICI) in cancer. However, the contribution of genetic, immune, and (micro)environmental factors to TLS formation and function remain incompletely understood. Using harmonized bulk and single-cell RNA-sequencing c...

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Literature Corpus work: 6cfb5389-307d-5932-8516-6ab8e981609e
DOI: 10.1101/2025.08.20.671212

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