Back to search

Article

Tertiary lymphoid structures critical for prognosis in endometrial cancer patients - a TransPORTEC study

2021-07-13

Abstract excerpt

<title>Abstract</title> <p>B-cells play a key role in cancer suppression, particularly when aggregated in tertiary lymphoid structures (TLS). Here, we investigated the role of B-cells and TLS in endometrial cancer (EC). Single cell RNA-sequencing of B-cells showed presence of activated/memory B-cells, cycling/germinal center B-cells and antibody-secreting cells. Differential gene expression analysis showed associ...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8bf0181e-3f8a-53ca-98ff-5f08a41f0d5b
DOI
10.21203/rs.3.rs-677975/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Tertiary lymphoid structures critical for prognosis in endometrial cancer patients - a TransPORTEC studyDOI 10.21203/rs.3.rs-677975/v1
Characteristics and Significance of Tertiary Lymphoid Structures Based on Molecular Subtypes in Endometrial Cancer.Semantic proximity
The landscape of tertiary lymphoid structures in endometrial cancer revealed through harmonized multi-level transcriptomicsSemantic proximity
Tertiary lymphoid structures critical for the prognosis of patients with cervical cancerSemantic proximity
Immunological profiling of molecularly classified high-risk endometrial cancers identifies POLE-mutant and microsatellite unstable carcinomas as candidates for checkpoint inhibitionSemantic proximity
New therapeutic targets for endometrial cancer: a glimpse into the preclinical sphere.Semantic proximity
CXCL9 and CXCL13 coordinately shape the immune-activated microenvironment of endometrial cancer via tertiary lymphoid structure formationSemantic proximity
The Clinical and Pathological Characteristics of POLE-Mutated Endometrial Cancer: A Comprehensive ReviewSemantic proximity
Checkpoint inhibitors in endometrial cancer: preclinical rationale and clinical activitySemantic proximity
Enhanced risk stratification in early-stage endometrial cancer: Integrating Molucular-L1CAM Classification and Simplified L1CAM/p53 CategorizationSemantic proximity
Tumor immune microenvironment in endometrial cancer of different molecular subtypes: evidence from a retrospective observational study.Semantic proximity
Impact of molecular profile on prognosis and relapse pattern in low and intermediate risk endometrial cancer.Semantic proximity
Enhanced Risk Stratification in Early-Stage Endometrial Cancer: Integrating POLE through Droplet Digital PCR and L1CAMSemantic proximity
Select a neighboring publication to make it the new centre.