Article

Pulses of RhoA Signaling Stimulate Actin Polymerization and Flow in Protrusions to Drive Collective Cell Migration

2023-10-05

Abstract excerpt

<h4>Summary</h4> In animals, cells often move as collectives to shape organs, close wounds, or—in the case of disease—metastasize. To accomplish this, cells need to generate force to propel themselves forward. The motility of singly migrating cells is driven largely by an interplay between Rho GTPase signaling and the actin network (Yamada and Sixt, 2019). Whether cells migrating as collectives use the same machi...

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Literature Corpus work: 6cdfcc7c-4b69-5dfd-929d-72c1aae0dad5
DOI: 10.1101/2023.10.03.560679

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