Genetic influences on circulating retinol and its relationship to human health

Abstract excerpt

<h4>ABSTRACT</h4> Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Previous work has characterised genetic influences on circulating retinol; however, small sample sizes have limited our ability to fully appreciate the genetic architecture of this trait. In this study, we performed the largest genome-wide association study (GWAS) of retinol t...

Topics

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• Adiposity
• Genome-Wide Association Study
• Mendelian Randomization Analysis
• Obesity
• Phenotype
• Polymorphism, Single Nucleotide
• Retinol-Binding Proteins, Plasma
• Vitamin A

Identifiers and source

Literature Corpus work

6ccb7554-25dc-5bda-ac67-bdec700c04ae

DOI

10.1101/2023.08.07.23293796