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Article

The causal role of circulating vitamin D concentrations in human complex traits and diseases: a large-scale Mendelian randomization study.

Scientific reports - 8 Jan 2021

Jiang Xia, Ge Tian, Chen Chia-Yen

Abstract excerpt

Vitamin D has been associated with a variety of human complex traits and diseases in observational studies, but a causal relationship remains unclear. To examine a putative causal effect of vitamin D across phenotypic domains and disease categories, we conducted Mendelian randomization (MR) analyses using genetic instruments associated with circulating 25-hydroxyvitamin D [25(OH)D] concentrations. We leveraged...

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Identifiers

PMID: 33420236
DOI: 10.1038/s41598-020-80655-w
PMCID: PMC7794542

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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