Article

Cellular genome wide association study identifies common genetic variation influencing lithium induced neural progenitor proliferation

2022-02-02

Abstract excerpt

Lithium is used in the treatment of bipolar disorder (BD) and is known to increase neural progenitor cell (NPC) proliferation. Though the mechanism of lithium’s therapeutic effect is not understood, evidence suggests that genetic variation influences response to treatment. Here, we used a library of genetically diverse human NPCs to identify common genetic variants that modulate lithium induced proliferation. We i...

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Literature Corpus work: 6c858adc-7908-5289-9c00-e0933021654c
DOI: 10.1101/2022.01.31.478307

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