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Article

Cellular Genome-wide Association Study Identifies Common Genetic Variation Influencing Lithium-Induced Neural Progenitor Proliferation.

Biological psychiatry - 1 Jan 2023

Wolter Justin M, Le Brandon D, Matoba Nana, Lafferty Michael J, Aygün Nil, Liang Dan, Courtney Kenan, Song Juan, Piven Joseph, Zylka Mark J, Stein Jason L

Abstract excerpt

BACKGROUND: Bipolar disorder is a highly heritable neuropsychiatric condition affecting more than 1% of the human population. Lithium salts are commonly prescribed as a mood stabilizer for individuals with bipolar disorder. Lithium is clinically effective in approximately half of treated individuals, and their genetic backgrounds are known to influence treatment outcomes. While the mechanism of lithium's...

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Identifiers

PMID: 36307327
DOI: 10.1016/j.biopsych.2022.08.014
PMCID: PMC9982734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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