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Article

Women's reproductive traits and major depressive disorder: A two-sample Mendelian randomization study.

Journal of affective disorders - 1 Apr 2023

Wang Zhenqian, Lu Jiawen, Weng Weipin, Fu Jianhan, Zhang Jie

Abstract excerpt

BACKGROUND: Evidence suggested strong associations between women's reproductive factors and major depressive disorder (MDD), but their causalities are unclear. METHODS: Using female-specific SNPs as genetic instruments obtained from large-scale genome-wide association studies for women's reproductive traits, we designed two-sample univariable and multivariable Mendelian randomization (MR) analysis to evaluate the...

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Identifiers

PMID: 36682697
DOI: 10.1016/j.jad.2023.01.063

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