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The role of sex hormones in severe mental illness: A genetic exploration.

Psychoneuroendocrinology - 1 May 2026

Veeneman R R, Verweij K J H, Sommer I E C, Treur J L, Vermeulen J M

Abstract excerpt

INTRODUCTION: Prominent sex differences exist in severe mental illness (SMI), with increasing evidence pointing towards a pivotal role for sex hormones. Elucidation of these hormonal influences is crucial to tailor sex-specific prevention and treatment. METHODS: To investigate potential shared genetics and bi-directional causal effects between sex hormone traits and SMI (depressive disorder, bipolar disorder and...

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Depressive Disorder
Estrogens
Gonadal Steroid Hormones
Mental Disorders
Progesterone

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Sex Hormone-Binding Globulin

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PMID: 41762828
DOI: 10.1016/j.psyneuen.2026.107810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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