Article

Genetic variants within silencer elements contribute to human blood cell traits

2025-01-14

Abstract excerpt

Genome-wide association studies (GWAS) have identified numerous non-coding loci associated with human complex traits and diseases. However, assigning the functional impacts to the underlying variants remains challenging. In this study, we performed high-throughput ReSE screening to characterize the effects of 14,720 fine-mapped causal non-coding SNPs associated with 15 diverse blood traits on the potential silence...

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Literature Corpus work: f31abc84-8e2f-51d6-81a6-5ba60c0aa89e
DOI: 10.1101/2025.01.13.632723

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