Article

Polyunsaturated fatty acid-derived lipid mediator networks characterize COVID-19 severity and risk for critical illness

2024-08-28

Abstract excerpt

Severe COVID-19 is characterized by excessive inflammation leading to the development of pneumonia and acute respiratory distress syndrome. Bioactive lipid mediators (LMs) derived from ω6 and ω3 polyunsaturated fatty acids are central to the regulation of inflammation, controlling both its initiation and resolution. Still, their role in COVID-19 remains underexplored. By employing a holistic approach involving the...

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Literature Corpus work: 6be23958-ab4a-5bbf-b270-635b86f22089
DOI: 10.1101/2024.08.28.610123

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