Article

Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infection

2023-09-15

Abstract excerpt

<h4>Background</h4> Many questions remain unanswered regarding the implication of lipid metabolites in severe SARS-CoV-2 infections. By re-analyzed sequencing data from the nasopharynx of a previously published cohort, we found that alox genes, involved in eicosanoid synthesis, were up-regulated in high WHO score patients, especially in goblet cells. Herein, we aimed to further understand the roles played by eicos...

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Literature Corpus work: f8c5b8f4-36f9-54b3-aeca-a0910bd4342d
DOI: 10.1101/2023.09.14.23295549

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Enhanced production of eicosanoids in plasma and activation of DNA damage pathways in PBMCs are correlated with the severity of ancestral COVID-19 infectionDOI 10.1101/2023.09.14.23295549Read

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