Back to search

Article

Postpartum Plasma-Derived Exosomes Confer Mitochondrial Stabilization and Neuroprotection against Ischemic Stroke

2026-05-27

Abstract excerpt

<title>Abstract</title> <p> Background The molecular mechanisms governing adaptive neuroprotection during the postpartum period remain unknown. We hypothesized that circulating exosomes contain bioactive cargo (such as Hsp20) that confer neuroprotection against ischemic injury during the postpartum period. Methods Exosomes were isolated from plasma of postpartum female mice (ppExos) and control female mice, an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
6bdf1ca6-2357-524d-9f7d-3d3ad26e1a48
DOI
10.21203/rs.3.rs-9573067/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Postpartum Plasma-Derived Exosomes Confer Mitochondrial Stabilization and Neuroprotection against Ischemic StrokeDOI 10.21203/rs.3.rs-9573067/v1
Stroke in Pregnancy Brings Epigenetic Changes in Correlation with Affected Mitochondrial Dynamics and Inflammasome Mediated Apoptosis in RodentsSemantic proximity
Streamlined Analysis of Maternal Plasma Indicates Small Extracellular Vesicles are Significantly Elevated in Early-Onset PreeclampsiaSemantic proximity
Novel window on early human neurodevelopment via fetal exosomes in maternal bloodSemantic proximity
NSC-derived exosomes enhance therapeutic effects of NSC transplantation on cerebral ischemia in miceSemantic proximity
Multiplexed mRNA analysis of brain-derived extracellular vesicles upon experimental stroke in mice reveals increased mRNA content related to inflammation and recovery processesSemantic proximity
Microglia-derived iron-overloaded exosomes induce neuronal ferroptosis and aggravate neurological impairment after subarachnoid hemorrhageSemantic proximity
Serum Exosomes from a Uniquely Defined Early-Adult Donor Cohort Reprogram Endothelial Transcriptomes Linked to Alzheimer’s PathogenesisSemantic proximity
Sex differences in the effects of PARP inhibition on microglial phenotypes following neonatal stroke.Semantic proximity
Bone marrow mesenchymal stem cell-derived exosomes attenuate cerebral ischemia-reperfusion injury-induced neuroinflammation and pyroptosis by modulating microglia M1/M2 phenotypes.Semantic proximity
miR-137 boosts the neuroprotective effect of endothelial progenitor cell-derived exosomes in oxyhemoglobin-treated SH-SY5Y cells partially via COX2/PGE2 pathwaySemantic proximity
Early treatment with exosomes following traumatic brain injury and hemorrhagic shock in a swine model promotes transcriptional changes associated with neuroprotectionSemantic proximity
Cardioprotection by cardiac progenitor cell-secreted exosomes: role of pregnancy-associated plasma protein-A.Semantic proximity
Select a neighboring publication to make it the new centre.