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Article

Novel window on early human neurodevelopment via fetal exosomes in maternal blood

25 Feb 2016

Abstract excerpt

Adverse in utero exposures can disrupt fetal brain development, deplete subpopulations of neurons and inhibit formation of normal synaptic connections. A major roadblock to unraveling the precise mechanisms and timing of human neurodevelopmental derangement is the almost complete absence of sensitive noninvasive assessments. We present novel methods for isolating fetal neuronal exosomes from maternal plasma as a...

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PMID: 27231707
DOI: 10.1002/acn3.296

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