Article

Cancer cachexia is regulated by selective targeting of skeletal muscle gene products

2004-08-01

Abstract excerpt

Cachexia is a syndrome characterized by wasting of skeletal muscle and contributes to nearly one-third of all cancer deaths. Cytokines and tumor factors mediate wasting by suppressing muscle gene products, but exactly which products are targeted by these cachectic factors is not well understood. Because of their functional relevance to muscle architecture, such targets are presumed to represent myofibrillar protei...

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Identifiers and source

Literature Corpus work: 6bc7bd42-19b5-5ba2-9589-81e0a1370855
DOI: 10.1172/jci200420174

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