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HMGB1 assists in overcoming cisplatin resistance in chemoresistant human ovarian cancer cells

2025-09-27

Abstract excerpt

Cisplatin is one of the most effective chemotherapeutic agents used in the treatment of ovarian cancer. However, the frequent development of cisplatin resistance remains a significant limitation, leading to therapeutic failure and poor patient outcomes. Cisplatin cytotoxicity is attributed to the generation of toxic DNA lesions, which can be recognized and processed by a variety of proteins, including the high mob...

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Identifiers and source

Literature Corpus work
6bb0e169-71fe-5573-b6ea-688847936733
DOI
10.1101/2025.09.25.678487
Open publication

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HMGB1 assists in overcoming cisplatin resistance in chemoresistant human ovarian cancer cellsDOI 10.1101/2025.09.25.678487
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