Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)

29 Jun 2023

Abstract excerpt

Tumor multidrug resistance (MDR) remains one of the most challenging barriers to successful cancer treatment. Several previous studies have suggested that high mobility group box 1 (HMGB1) may be a promising therapeutic target for overcoming cancer drug resistance. Emerging evidence has indicated that HMGB1 functions as a 'double‑edged sword' that plays both pro‑ and anti‑tumor roles in the development and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ferroptosis and cancer prognosis
Share to MicroRNA in disease regulation
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37387415
DOI: 10.3892/ijmm.2023.5272

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms involved in the HMGB1 modulation of tumor multidrug resistance (Review)PMID 37387415Read ↗

HMGB1 Promotes Drug Resistance in OsteosarcomaSemantic proximity Read ↗

Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity Read ↗

Multiple functions of HMGB1 in cancerSemantic proximity Read ↗

The progression of HMGB1-induced autophagy in cancer biologySemantic proximity Read ↗

miR-22 targets the 3′ UTR of HMGB1 and inhibits the HMGB1-associated autophagy in osteosarcoma cells during chemotherapySemantic proximity Read ↗

The dual role and therapeutic potential of high-mobility group box 1 in cancerSemantic proximity Read ↗

High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesSemantic proximity Read ↗

Masquerader: High Mobility Group Box-1 and CancerSemantic proximity Read ↗

High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity Read ↗

HMGB1 in the interplay between autophagy and apoptosis in cancerSemantic proximity Read ↗

HMGB1 assists in overcoming cisplatin resistance in chemoresistant human ovarian cancer cellsSemantic proximity Read ↗

Emerging roles for HMGB1 protein in immunity, inflammation, and cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.