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Article

Association Of Plasma And Urinary Mutant DNA With Clinical Outcomes In Muscle Invasive Bladder Cancer.

Scientific reports - 17 Jul 2017

Patel K M, van der Vos K E, Smith C G, Mouliere F, Tsui D, Morris J, Chandrananda D, Marass F, van den Broek D, Neal D E, Gnanapragasam V J, Forshew T, van Rhijn B W, Massie C E, Rosenfeld N, van der Heijden M S

Abstract excerpt

Muscle Invasive Bladder Cancer (MIBC) has a poor prognosis. Whilst patients can achieve a 6% improvement in overall survival with Neo-Adjuvant Chemotherapy (NAC), many do not respond. Body fluid mutant DNA (mutDNA) may allow non-invasive identification of treatment failure. We collected 248 liquid biopsy samples including plasma, cell pellet (UCP) and supernatant (USN) from spun urine, from 17 patients undergoing...

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Identifiers

PMID: 28717136
DOI: 10.1038/s41598-017-05623-3
PMCID: PMC5514073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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