Article

NK Cell Adoptive Transfer Suppresses Metastasis and Prolongs Survival in Pancreatic Cancer

2026-05-19

Abstract excerpt

<title>Abstract</title> <p>Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest malignancies, with metastatic disease accounting for nearly 90% of these deaths and no therapies that effectively prevent metastatic progression. Here, we identify natural killer (NK) cells as central regulators of metastatic competence in PDAC, actively constraining dissemination and preventing tumor-intrinsic reprogramming...

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Literature Corpus work: 6b8d2ee1-c203-5917-853f-a661e4c18137
DOI: 10.21203/rs.3.rs-9082655/v1

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