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Article

Epigenetic Signatures of Salivary Gland Inflammation in Sjögren's Syndrome.

Arthritis & rheumatology (Hoboken, N.J.) - 1 Dec 2016

Cole Michael B, Quach Hong, Quach Diana, Baker Alice, Taylor Kimberly E, Barcellos Lisa F, Criswell Lindsey A

Abstract excerpt

OBJECTIVE: Sjögren's syndrome (SS) is a complex multisystem autoimmune disease that results in progressive destruction of the exocrine glands. The purpose of this study was to characterize epigenetic changes in affected gland tissue and describe the relationship of these changes to known inflammatory processes. METHODS: A genome-wide DNA methylation study was performed on human labial salivary gland (LSG) biopsy...

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Share to Antigen-Presenting Cells
Share to ATP Binding Cassette Transporter, Subfamily B, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intracellular Signaling Peptides and Proteins

Share to Principal Component Analysis

Share to Proteasome Endopeptidase Complex

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Share to Transmembrane Activator and CAML Interactor Protein

Source

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Identifiers

PMID: 27332624
DOI: 10.1002/art.39792
PMCID: PMC5132022

Genes

PSMB8
TAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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