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Article

Linking genetic variation with epigenetic profiles in Sjögren's syndrome.

Clinical immunology (Orlando, Fla.) - 1 Jan 2020

Arvaniti Pinelopi, Le Dantec Christelle, Charras Amandine, Arleevskaya Marina A, Hedrich Christian M, Zachou Kalliopi, Dalekos George N, Renaudineau Yves

Abstract excerpt

DNA methylation represents an important regulatory event governing gene expression that is dysregulated in Sjögren's syndrome (SjS) and a number of autoimmune/inflammatory diseases. As disease-associated single-nucleotide polymorphisms (SNPs) have relevance in controlling DNA methylation, 94 non-HLA SjS-SNPs were investigated, among them 57 (60.6%) with widespread effects on 197 individual DNA methylation...

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Identifiers

PMID: 31765834
DOI: 10.1016/j.clim.2019.108314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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