Article

Osmolytes and Macromolecular Crowders Diversely Affect the Aggregation of the Cancerrelated L106R Mutant of the Axin RGS Domain

2020-10-06

Abstract excerpt

Protein aggregation is involved in a variety of diseases, including neurodegenerative diseases and cancer. The cellular environment is crowded by a plethora of cosolutes comprising small molecules and biomacromolecules at high concentrations, which may influence the aggregation of proteins in vivo . To account for the effect of cosolutes on cancer-related protein aggregation, we studied their effect on the...

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Literature Corpus work: 6b369b9b-d23f-5540-bda5-66b309d00549
DOI: 10.26434/chemrxiv.13055507.v1

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Osmolytes and Macromolecular Crowders Diversely Affect the Aggregation of the Cancerrelated L106R Mutant of the Axin RGS DomainDOI 10.26434/chemrxiv.13055507.v1Read

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