Article
Cryo-EM and cryo-ET reveal the molecular architecture and host interactions of mycobacteriophage Douge
24 Jul 2025
Abstract excerpt
Recent reports highlight the efficacy of engineered mycobacteriophages to treat non-tuberculosis mycobacterial disease. Molecular insights into mycobacteriophage architecture and host interactions could allow structure-guided phage engineering to increase efficacy and broaden host range, but such information is currently unavailable. We describe the cryoelectron microscopy (cryo-EM) structure of mycobacteriophage...
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