Article

High-resolution cryo-EM analysis of the therapeutic <i>Pseudomonas</i> phage Pa223

2025-06-12

Abstract excerpt

<h4>ABSTRACT</h4> Cryogenic electron microscopy (cryo-EM) analysis of bacteriophages is a valuable method for deciphering virus composition and conformational plasticity. In this study, we present a high-resolution structural atlas of the Pseudomonas virus Pa223, a phage from the Bruynoghevirus genus that has recently been used in clinical cocktails for treating cystic fibrosis and non-cystic fibrosis bronchiec...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 48905b49-305c-535c-9266-6bc9d626b7a3
DOI: 10.1101/2025.06.11.659172

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

High-resolution cryo-EM analysis of the therapeutic <i>Pseudomonas</i> phage Pa223DOI 10.1101/2025.06.11.659172Read

Cryo-EM analysis of Pseudomonas phage Pa193 structural componentsSemantic proximity Read

Insights into Genome Ejection by a Therapeutic phiKMV-like BacteriophageSemantic proximity Read

Chaperone-assisted cryo-EM structure of <i>P. aeruginosa</i> PhuR reveals molecular basis for heme bindingSemantic proximity Read

Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human PicobirnavirusSemantic proximity Read

Structural atlas of the most abundant human gut virusSemantic proximity Read

Structural basis for repurposing a flexible phage tail into an Intraspecific bacterial competition weaponSemantic proximity Read

Complexity and ultrastructure of infectious extracellular vesicles from cells infected by non-enveloped virusSemantic proximity Read

From cells to atoms: Cryo‐EM as an essential tool to investigate pathogen biology, host–pathogen interaction, and drug discoverySemantic proximity Read

Cryo-EM and cryo-ET reveal the molecular architecture and host interactions of mycobacteriophage DougeSemantic proximity Read

Structure and size determination of bacteriophage P2 and P4 procapsids: function of size responsiveness mutations.Semantic proximity Read

Structure of the virulence-associated <i>Neisseria meningitidis</i> filamentous bacteriophage MDAΦSemantic proximity Read

Structure of the <i>Staphylococcus aureus</i> bacteriophage 80α neck shows the interactions between DNA, tail completion protein and tape measure proteinSemantic proximity Read