Article

Genetic interaction of <em>Thm2</em> and <em>Thm1</em> Shapes Postnatal Craniofacial Bone

2022-04-16

Abstract excerpt

Ciliopathies are genetic syndromes that link skeletal dysplasias to dysfunction of primary cilia. Primary cilia are sensory organelles synthesized by intraflagellar transport (IFT) - A and B complexes, which traffic protein cargo along a microtubular core. We have reported that deletion of IFT-A gene, Thm2, together with a null allele of its paralog, Thm1, causes a small skeleton with small mandible or micrognathi...

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Literature Corpus work: 6aaf4d38-f8f9-5bba-91ee-cda60cad9028
DOI: 10.20944/preprints202204.0150.v1

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