Article
Unmasking the ciliopathies: craniofacial defects and the primary cilium.
Wiley interdisciplinary reviews. Developmental biology - 1 Jan 2000
Cortés Claudio R, Metzis Vicki, Wicking Carol
Abstract excerpt
Over the past decade, the primary cilium has emerged as a pivotal sensory organelle that acts as a major signaling hub for a number of developmental signaling pathways. In that time, a vast number of proteins involved in trafficking and signaling have been linked to ciliary assembly and/or function, demonstrating the importance of this organelle during embryonic development. Given the central role of the primary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.