Article

“A transient heritable memory regulates HIV reactivation from latency”

2020-07-02

Abstract excerpt

Reactivation of human immunodeficiency virus 1 (HIV-1) from latently infected T cells is a critical barrier to successfully eradicate HIV-1 from patients. Latency models in Jurkat T-cells reveal that individual cells reactivate in an all-or-none fashion when exposed to latency reversal agents (LRAs). Remarkably, this heterogeneity arises within a clonal cell population of genetically identical cells containing a s...

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Literature Corpus work: 6a5fb20e-d5ab-54eb-9fc5-967c93b199b1
DOI: 10.1101/2020.07.02.185215

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