Article
A minimal fate-selection switch.
Current opinion in cell biology - 1 Dec 2015
Weinberger Leor S
Abstract excerpt
To preserve fitness in unpredictable, fluctuating environments, a range of biological systems probabilistically generate variant phenotypes--a process often referred to as 'bet-hedging', after the financial practice of diversifying assets to minimize risk in volatile markets. The molecular mechanisms enabling bet-hedging have remained elusive. Here, we review how HIV makes a bet-hedging decision between active...
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