Article

Investigation of Lung-Blood Interplays in COVID-19 Cytokine Storm Using Gene Co-Expression and Protein-Protein Interaction Networks

2026-03-26

Abstract excerpt

<h4>Background: </h4> Several SARS-CoV-2 patients experience severe lung disease that can progress to multiple organ failure and death due to dysregulated cytokine release, known as a “cytokine storm.” Although cytokine storms were first described in 1993, their underlying mechanisms remain incompletely understood. Methods Lung and blood transcriptomic gene co-expression networks were constructed to identify gene...

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Literature Corpus work: 6a5aac02-2846-5e48-abbf-adfa8d588c8a
DOI: 10.12688/f1000research.178200.1

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