Article

Host transcriptomic profiling of COVID-19 patients with mild, moderate, and severe clinical outcomes

2020-09-28

Abstract excerpt

Characterizing key molecular and cellular pathways involved in COVID-19 is essential for disease prognosis and management. We perform shotgun transcriptome sequencing of human RNA obtained from nasopharyngeal swabs of patients with COVID-19, and identify a molecular signature associated with disease severity. Specifically, we identify globally dysregulated immune related pathways, such as cytokine-cytokine recepto...

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Literature Corpus work: 3994ce78-f6a8-565a-9f92-44e67db26425
DOI: 10.1101/2020.09.28.316604

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