Article

Ligand/Receptor-mediated Cell Communication Alteration Causes the Lung Inflammation Microenvironment and the Redistribution of Inter-tissue Immune Cells in COVID-19 Patients

2022-03-21

Abstract excerpt

<title>Abstract</title> <p>How SARS-CoV-2 causes disturbances of the lung microenvironment and systemic immune response remains a mystery. Here, we first analyze detailedly paired single-cell transcriptome data of the lungs, blood and bone marrow of two patients who died of COVID-19. Second, our results demonstrate that SARS-CoV-2 infection significantly increases the cellular communication frequency between AT1/...

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Literature Corpus work: bbc3d655-6c8b-5730-b156-272af72acbfd
DOI: 10.21203/rs.3.rs-1442272/v1

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