Article

Mitochondrial genome variants associated with Amyotrophic Lateral Sclerosis and their haplogroup distribution

2024-04-25

Abstract excerpt

<h4>Introduction/Aims</h4> Amyotrophic lateral sclerosis (ALS) may be familial or sporadic, and twin studies have revealed that even sporadic forms have a significant genetic component. Variants in 55 nuclear genes have been associated with ALS and although mitochondrial disfunction is observed in ALS, variants in mitochondrial genomes (mitogenomes) have not yet been tested for association with ALS. <h4>Methods</h...

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Literature Corpus work: f0e2617d-78c7-5743-b971-f84d5f3d88bf
DOI: 10.1101/2024.04.23.24306232

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