Article

Fibroblast growth factor receptor type 4 as a potential therapeutic target in clear cell renal cell carcinoma

2022-11-23

Abstract excerpt

<h4>Background: </h4> Several clear cell renal cell carcinoma (ccRCC) cases harbour fibroblast growth factor receptor 4 ( FGFR4 ) gene copy number (CN) gains. In this study, we investigated the functional contribution of FGFR4 CN amplification in ccRCC. Methods The correlation between FGFR4 CN determined via real-time PCR and protein expression evaluated by western blotting and immunohistochemistry was assessed i...

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Literature Corpus work: 6a42460b-e16d-5b07-8633-3d47a3fbc4e1
DOI: 10.21203/rs.3.rs-2190717/v1

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