Article

HER2 in Clear Cell Renal Cell Carcinoma: Expression and Novel Targeting

2025-10-14

Abstract excerpt

<h4>Purpose: </h4> The HER2 oncoprotein, a membrane-associated protein with tyrosine kinase activity, is overexpressed in many solid tumours. Its overexpression is associated with poor prognosis and disease progression. In kidney cancer, there is no molecular marker to guide patient treatment and prognosis. <h4>Materials and Methods:</h4> For the study, 110 biopsy samples obtained from patients with renal epitheli...

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Literature Corpus work: 6023f300-9c73-5db7-b905-7407edbce7e8
DOI: 10.20944/preprints202510.1095.v1

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