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Article

Noninvasive Imaging of the Transcriptional Activities of Human Telomerase Promoter Fragments in Mice

15 Jul 2004

Abstract excerpt

We have assessed the feasibility of positron emission tomography (PET) and ex vivo gamma-counting to measure the pattern of expression of telomerase promoter fragments in vivo. Promoter fragments from either the RNA [human telomerase RNA (hTR)] or the catalytic components [human telomerase reverse transcriptase (hTERT)] of the telomerase genes were used to drive the expression of the sodium iodide symporter PET...

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Share to RNA Interference and Gene Delivery
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PMID: 15256462
DOI: 10.1158/0008-5472.can-04-0426

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