Article

Quantification of heterogeneity in human CD8 <sup>+</sup> T cell responses to vaccine antigens: an HLA-guided perspective

2024-07-03

Abstract excerpt

<h4>ABSTRACT</h4> Vaccines have historically played a pivotal role in controlling epidemics. Effective vaccines for viruses causing significant human disease, e.g ., Ebola, Lassa fever, or Crimean Congo hemorrhagic fever virus, would be invaluable to public health strategies and counter-measure development missions. Here, we propose coverage metrics to quantify vaccine-induced CD8 + T cell-mediated immune prote...

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Literature Corpus work: 6a214257-ce98-5dde-ab35-fc069d3ad45f
DOI: 10.1101/2024.07.02.601716

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