Article
A Bioinformatic Investigation of Proteasome And Autophagy Expression in The Central Nervous System
2021-12-01
Abstract excerpt
The ubiquitin proteasome system (UPS) and autophagy lysosome pathway (ALP) play major roles in protein quality control. However, data regarding the relative significance of UPS and ALP in the central nervous system (CNS) remain limited. In this study, we reckon the quantitative expression status of UPS- and ALP-related genes and their products in the CNS compared to that in other tissues. We collected human and mo...
Topics
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- Alzheimer's disease research and treatments
- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- Muscle Physiology and Disorders
- Neurogenetic and Muscular Disorders Research
- Neurological diseases and metabolism
- Parkinson's Disease Mechanisms and Treatments
- Ubiquitin and proteasome pathways
Identifiers and source
- Literature Corpus work
- 69c11edf-e7a2-553b-ab49-9bbb469103a1
- DOI
- 10.21203/rs.3.rs-1069750/v1
