Article

Genetic determinants of COVID-19 drug efficacy revealed by genome-wide CRISPR screens

2020-10-27

Abstract excerpt

Immunomodulatory agents dexamethasone and colchicine, antiviral drugs remdesivir, favipiravir and ribavirin, as well as antimalarial drugs chloroquine phosphate and hydroxychloroquine are currently used in the combat against COVID-19 1–16 . However, whether some of these drugs have clinical efficacy for COVID-19 is under debate. Moreover, these drugs are applied in COVID-19 patients with little knowledge of genet...

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Literature Corpus work: 69a400b2-dc66-5f25-b702-f9b828c97d13
DOI: 10.1101/2020.10.26.356279

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