Article
Pharmacogenomic considerations for repurposing of dexamethasone as a potential drug against SARS-CoV-2 infection.
Personalized medicine - 1 Jul 2021
Vohra Manik, Sharma Anu Radha, Satyamoorthy Kapaettu, Rai Padmalatha S
Abstract excerpt
Immunomodulatory and analgesic effects of dexamethasone are clinically well established, and this synthetic corticosteroid acts as an agonist of glucocorticoid receptors. Early results of the RECOVERY Trial from the United Kingdom and others suggest certain benefits of dexamethasone against COVID-19 chronic patients. The efforts have been acknowledged by World Health Organization with an interim guideline to use...
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