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Article

Antioxidant paraoxonase 1 activity in the metabolic syndrome.

The Journal of clinical endocrinology and metabolism - 1 Nov 2003

Sentí Mariano, Tomás Marta, Fitó Montserrat, Weinbrenner Tanja, Covas María-Isabel, Sala Joan, Masiá Rafel, Marrugat Jaume

Abstract excerpt

Paraoxonase (PON1) is an antioxidant enzyme closely associated with high-density lipoproteins. Low PON1 has been shown in oxidative stress-associated processes such as dyslipidemia, diabetes mellitus, advancing age, and smoking. Indeed, oxidative stress is related to the degree of insulin resistance, a key component of the metabolic syndrome. Therefore, the possible relationship between PON1 activity and the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14602783
DOI: 10.1210/jc.2003-030648

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Antioxidant paraoxonase 1 activity in the metabolic syndrome.PMID 14602783Read ↗

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Enzyme Activity and Genetic Polymorphisms of Paraoxonase 1 in Patients With Type 2 Diabetes Mellitus: A Case-Control StudySemantic proximity Read ↗

Paraoxonase (PON)-1: a brief overview on genetics, structure, polymorphisms and clinical relevance.Semantic proximity Read ↗

Dissecting PON1 Genotype Combinations Modulating Paraoxonase Activity and Risk of Dysglycemia and Liver FibrosisSemantic proximity Read ↗

The Molecular Bases of Anti-oxidative and Anti-inflammatory Properties of Paraoxonase 1Semantic proximity Read ↗

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