Article

Clinical Relevance of BCL2, BCL6, and MYC Rearrangements in Diffuse Large B-Cell Lymphoma

1998-11-01

Abstract excerpt

Diffuse large B-cell lymphoma (DLCL) is characterized by a marked degree of morphologic and clinical heterogeneity. We studied 156 patients with de novo DLCL for rearrangements of the BCL2, BCL6, and MYC oncogenes by Southern blot analysis and BCL2 protein expression. We related these data to the primary site of presentation, disease stage, and other clinical risk factors. Structural alterations of BCL2, BCL6, and...

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Literature Corpus work: 696746d0-6e0f-5ecd-9fa7-a7cd669dd2dd
DOI: 10.1182/blood.v92.9.3152.421a07_3152_3162

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