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Article

MYC alterations in diffuse large B-cell lymphomas.

Seminars in hematology - 1 Apr 2015

Karube Kennosuke, Campo Elias

Abstract excerpt

MYC is a transcription factor associated with numerous physiological functions, including apoptosis, and strong oncogenic potential. MYC expression is tightly regulated in normal lymphoid cells with high levels in the initial steps of the secondary lymphoid follicle formation and in a subset of centrocytes of the germinal center light zone. BCL6 and BLIMP1 repress MYC expression in normal germinal center B and...

Read the complete abstract on PubMed

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Share to Genes, myc
Share to DNA-Binding Proteins
Share to BCL6 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphoma, Large B-Cell, Diffuse

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Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-bcl-6

Share to Translocation, Genetic

Source

Identifiers

PMID: 25805589
DOI: 10.1053/j.seminhematol.2015.01.009

Genes

MYC
BCL2
BCL6
IGH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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