Article

Modeling disease progression and placebo response in Huntington's Disease: Insights from Enroll-HD and GENERATION HD1 cohorts

2024-02-17

Abstract excerpt

<h4>Objective: </h4> The objective of this study was to quantify longitudinal changes in Unified Huntington's Disease Rating Scale (UHDRS) clinical scores and evaluate their susceptibility to placebo response, improving our understanding of disease progression and the ability to optimize clinical trials in Huntington's disease. <h4>Methods:</h4> We utilized data from the Enroll-HD and GENERATION HD1 placebo arm co...

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Literature Corpus work: 69582e1f-3d8b-5fa8-a693-c7da5a0854de
DOI: 10.1101/2024.02.15.24302445

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